IPAMORELIN
OVERVIEW
• Ipamorelin is the mildest of GHRPS (Growth Hormone Releasing
Peptide)
• Stimulates the release of growth hormone without an increase in
appetite, cortisol, or prolactin
• Higher doses do not lead to desensitization
HOW DOES IT WORK
• Ipamorelin works by inhibiting somatostatin in the hypothalamus
• Somatostatin is the rate-limiting effect that allows the release of
growth hormone
• By inhibiting somatostatin, it allows the body to release growth
hormone
RESEARCH BENEFITS
• Increase release of endogenous growth hormone
Promotes muscle growth
• Helps with mood and stress resilience
• Slows down aging
• Improves sleep
• Promotes a balanced inflammatory response
• Improves bone density
RESEARCH SIDE EFFECTS
• Redness, itchiness, and swelling of injection sites
• Water retention
• Facial flushing
INSIGHT RESEARCH CYCLING & DOSING
• 100 mcg per injection is the starting dose
•Multiple injections can be given a day to increase GH secretion.
Often used in bodybuilding
• 5 days on, 2 days off, 10-12 weeks on, 4-8 weeks off
• Carbohydrates and fatty acids can blunt growth hormone release.
Best taken 30 minutes before eating or 2 hours after eating
INSIGHT ON RESEARCH TIMING & BENEFITS
• Burning Fat
• Before a workout in a fasted state
• Building Muscle
• After a workout in a fasted state
• Sleep
• Before bed in a fasted state
• General Anti-Aging
• In the morning in a fasted state
PEPTIDES & SUPPLEMENTS TO STACK WITH
• Any GHRH (Tesamorelin, MOD-GRF, Sermorelin)
• BPC-157
• AOD-9604
• Semaglutide/Tirezeptide
• PEG-MGF
• Kisspeptin-10
• 5-Amino-1-MQ
• Natural Diuretic (reduces water retention)
• Masculine Medicine
PROS & CONS
PROS
• GHRP with a high safety profile
• Larger doses can be given without desensitization
CONS
• Mildest of the GHRPs
